نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج، ایران
2 استاد، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج، ایران
3 دانشیار، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی دانشگاه تهران، کرج، ایران
4 دانشیار، گروه علوم دامی، دانشکدۀ کشاورزی، دانشگاه شیراز، شیراز، ایران
5 دانشجوی دکتری، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی دانشگاه گرگان، گرگان، ایران
چکیده
هدف از این پژوهش بررسی تأثیر پرکاری درازمدت غدۀ تیروئید بر وزن بدن و تولید تخممرغ بود. همچنین ارتباط بین پرکاری تیروئید و برخی فراسنجههای تولیدمثلی بررسی شد. در این آزمایش 70 قطعه مرغ مادر گوشتی سویۀ کاب 500 در سن 47 هفتگی به شیوۀ تصادفی به دو گروه تیمار (پنج تکرار شامل هفت پرنده) تقسیم شدند. تیروکسین به مدت صد روز متوالی به شیوۀ دهانی به گروه پرکار تجویز شد (3/0 میلیگرم به ازای هر پرنده در روز)، وزن بدن و تولید تخممرغ به شیوۀ هفتگی محاسبه شدند. تأثیر پرکاری تیروئید بر غلظت پلاسمایی T4معنیدار بود؛ اما غلظت T3تحت تأثیر قرار نگرفت. نتایج نشان دادند، هورمونهای تیروئیدی تأثیر کاهشی قابل توجهی بر وزن بدن داشتند. هورمونهای تیروئیدی بر تولید تخممرغ تأثیر نداشتند، اما اثر برهمکنش تیمار و زمان (هفته) بر تولید تخممرغ معنیدار بود. وزن تخمدان و اویداکت بین مرغهای گروه شاهد و پرکار تفاوت نداشتند. تجویز تیروکسین به مرغهای مادر سبب کاهش قطر فولیکولهای F1شد.
کلیدواژهها
عنوان مقاله [English]
Effects of long-term hyperthyroidism on body weight, egg production and reproductive traits in breeder hens
نویسندگان [English]
- Fatemeh Saemi 1
- Ahmad Zareh Shahneh 2
- Mahdi Zhandi 3
- Amir Akhlaghi 4
- Sharif Rostami 5
1 Ph.D. Candidate, Department of Animal Science, University College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
2 Professor, Department of Animal Science, University College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
3 Associate Professor, Department of Animal Science, University College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
4 Associate professor, Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran
5 Ph.D. Candidate, Department of Animal Science, University College of Agriculture and Natural Resources, University of Gorgan, Gorgan, Iran
چکیده [English]
The aim of this experiment was to study the effects of long-term induced hyperthyroidism on the body weight and egg production. In addition the relationships between hyperthyroidism and some reproductive parameters were studied. A total of seventy 47-week-old Cobb 500 breeder hens were randomly allotted to two treatment groups (5 replicates of 7 hens each). Thyroxine was orally administered to the hyperthyroid group (0.3 mg/bird/day) for 100 consecutive days during which the body weight and egg production were recorded on a weekly basis. Effect of hyperthyroidism on plasma T4 levels was significant; but, the T3 level was not affected. Results indicated a significant decreasing effect of thyroid hormones on body weight. Thyroid hormones had no effect on egg production; however, the treatment × time (wk) interaction effect was significant on egg production. Ovarian and oviductal weight were not different between the control and hyperthyroid hens. Administration of thyroxine to breeder hens decreased the diameter of F1 follicles.
کلیدواژهها [English]
- Breeder hen
- ovarian follicle
- reproduction
- thyroid hormone
- Akhlaghi, A., Zamiri, M. J., Jafari Ahangari, Y., Nejati Javaremi, A., Rahimi Mianji, G., Mollasalehi, M. R., Shojaie, H., Akhlaghi, A. A., Deldar, H., Atashi, H., Ansari Pirsaraei, Z. & Zhandi, M. (2012). Maternal hyperthyroidism is associated with a decreased incidence of cold-induced ascites in broiler chickens. Poultry Science, 91, 1165-1172.
- Akhlaghi, A., Zare Shahneh, A.,Zamiri, M. J., Nejati Javaremi, A. & Rahimi Mianji, G. (2009). Effect of transient postpubertal hypo- and hyperthyroidism on reproductive parameters of Iranian broiler breeder hens. African Journal of Biotechnology, 8, 5602-5610.
- Asmundson, V. S. & Pinsky, P. (1935). The effect of the thyroid on the formation of the hen’s egg. Poultry Science, 14, 99-104.
- Bilezikian, J. P., Loeb, J. & Gammon, D. E. (1980). Induction of Sustained Hyperthyroidism and Hypothyroidism in the Turkey: Physiological and Biochemical Observations. Poultry Science, 59, 628-634.
- Boulakoud, M. S. & Goldsmith, A. R. (1991). Thyroxine treatment induces changes in hypothalamic gonadotrophin-releasing hormone characteristic of photorefractoriness in starlings (Sturnus vulgaris). General and Comparative Endocrinology, 82, 78-85.
- Decuypere, E., Buyse, J., Scanes, C. G., Huybrechts, L. & Kühn, E. R. (1987). Effects of hyper- or hypothyroid status on growth, adiposity and levels of growth hormone, somatomedin c and thyroid metabolism in broiler chickens. Reproduction Nutrition Development, 27, 555-565.
- Decuypere, E., Van As, P., Van der Geyten, S. & Darras, V. M. (2005). Thyroid hormone availability and activity in avian species: A review. Domestic Animal Endocrinology, 29, 63-77.
- Decuypere, E. & Verheyen, G. (1986). Physiological basis of induced moulting and tissue regeneration in fowls. Worlds Poultry Science Journal, 42, 56-66.
- Gilbert, A. (1971). The ovary. In: Bell, D.J. and Freeman, B.M. (eds) Physiology and Biochemistry of the Domestic Fowl, Vol. 3. Academic Press, London, pp. 1163-1202.
- Jacquet, J. M., Seigneurin, F. & De Reviers, M. (1993). Effect of thyroxine on testicular function, circulating luteinising hormone and pituitary sensitivity to luteinising hormone‐releasing hormone in the cockerel (Gallus domesticus). British Poultry Science, 34, 803-814.
- Lien, R. J. & Siopes, T. D. (1991). Influence of thyroidectomy on reproductive responses of male domestic turkeys (Meleagris gallopavo). British Poultry Science, 32, 405-415.
- McNabb, F. M. A. (2007). The Hypothalamic-pituitary-thyroid (HPT) axis in birds and its role in bird development and reproduction. Critical Reviews in Toxicology, 37, 163-193.
- McNabb, F. M.A. & King, D. B. (1993). Thyroid hormone effects on growth, development and metabolism. In: Pang PKT, Scanes, CG, Schreibman, MP (eds) The Endocrinology of Growth, Development, and Metabolism in Vertebrates, , Academic Press, New York, pp. 393-417.
- Moore, G. E., Harvey, S. Klandorf, H. & Goldspink, G. (1984). Muscle development in thyroidectomised chickens (Gallus domesticus). General and Comparative Endocrinology, 55, 195-199.
- NRC. (1994). Nutrient requirements for poultry. (National Research Council: New York).
- Rousseau, K., Le Belle, N., Sbaihi, M., Marchelidon, J., Schmitz, M. & Dufour, S. (2002). Evidence for a negative feedback in the control of eel growth hormone by thyroid hormones. Journal of Endocrinology, 175, 605-613.
- SAS. (2003). User’s Guide: Statistics, Version 9.1 Edition. Inst., Inc., Cary, NC.
- Sauer, M. J., Cookson, A. D., McDonald, B. J. & Foulkes, J. A. (1982). The use of enzyme immunoassay for the measurement of hormones with particular reference to the determination of progesterone in unextracted whole milk. In: Wardley RC and Crowther JR (eds) The ELISA, Martinus Nijhoff Publishers, Netherlands, pp: 271-296.
- Scanes, C. G., Marsh, J., Decuypere, E. & Rudas, P. (1983). Abnormalities in the plasma concentrations of thyroxine, triiodothyronine and growth hormone in sex-linked dwarf and autosomal dwarf White Leghorn domestic fowl (Gallus domesticus). Journal of Endocrinoogy, 97, 127-135.
- Sechman, A. (2013). The role of thyroid hormones in regulation of chicken ovarian steroidogenesis. General and Comparative Endocrinology, 190, 68-75.