Investigating on the fitness of the strategies to control the BVD infection in Holstein ‎race ‎

Document Type : Research Paper


1 Ph. D. Candidate, Department of Animal Science, University of Tehran Aras International Campus, Jolfa, Iran

2 Professor, College of Agriculture & Natural Resources, University of Tehran, Karaj, Iran‎

3 Associate Professor, College of Agriculture & Natural Resources, University of Tehran, Karaj, Iran‎

4 Assistant Professor, Quality Control Department, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and ‎Extension Organization (AREEO), Karaj, Iran‎

5 Associate Professor, Quality Control Department, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and ‎Extension Organization (AREEO), Karaj, Iran‎


This study was conducted to evaluate prevalence of BVD and the strategies which were applied for prevention of BVD over the past 50 years in some provinces of Iran. Blood samples of 500 Iranian Holstein race were randomly collected from three dairy farms located in Tehran, Isfahan and Qazvin provinces. BVD control protocols of these farms were recorded. ELISA technique was used to measure the antibody and antigen titers for BVD. RT-PCR technique was performed to investigate the presence and the type of virus in all samples. The prevalence of Ab-/ Ag-, Ab+/ Ag-, Ab-/ Ag+ and Ab-/ Ag+ were 10.2%, 78.8%, 7.2% and 3.8%, respectively. Furthermore, approximately 4.2% of the animals were PI and the prevalence of antibody and antigen titers had not significant difference in three provinces. All positive samples were BVDV type 1. Type 2 was not observed in this study. The results of the study indicated that the efficiency of the used protocols to control BVD diseases is not successful. So, to control the BVD, applying large management policies at the national level is fundamental beside the biosecurity strategies.


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