The effect of dietary Letrozole on plasma gonadotropin concentrations and some testicular histology parameters in 40 weeks old broiler breeder rooster

Document Type : Research Paper

Authors

1 Ph. D. Candidate, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

2 Associate Professor, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

3 Professor, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

Abstract

The current study was carried out to evaluate the effect of Letrozole feeding on plasma LH and FSH concentrations and testicular histology in Ross 308 broiler breeder roosters. Twenty 40-week old roosters were randomly divided into four groups, individually housed and fed different levels of capsulated Letrozole including 0 (L0), 0.5 (L0.5), 1 (L1) or 1.5 (L1.5) mg/bird/day for 12 consecutive weeks. Blood sampling was done on 1th, 3th, 5th, 7th and 9th weeks of trail. Testicular histology was assessed on samples from last week (12th) of experiment. According to the results, plasma LH and FSH levels, seminiferous tubule diameter and epithelium thickness as well as Leydig cell numbers were significantly increased in Letrozole treated groups compered to control group. The highest concentration of FSH and LH were recorded for L1 (10.39 ±0.11 and 2.93±0.08) and L1.5 (9.5±0.2 and 3.17±0.08) groups, respectively. Both L0.5 and L1 groups had significantly higher spermatogonial numbers than control group. However, blood vessel numbers were not significantly affected. In conclusion, orally feeding Letrozole (1 and 1.5 mg) could improve gonadotropin concentration and testicular histology parameters of male broiler breeders at 40 weeks of age. Further studied are needed to confirm these results and extend them to final fertility.

Keywords

References

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Iranian Journal of animal Science
Volume 48, Issue 2 - Serial Number 2
September 2017
Pages 175-183

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History

  • Receive Date: 22 April 2017
  • Revise Date: 29 May 2017
  • Accept Date: 31 May 2017

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