The aim of this study was to identify Single Nucleotide Polymorphism (SNP) associated with selected reproductive traits in Holstein dairy cattle. The interval between calving and the first insemination, days open, the interval between the first and last insemination, and the number of inseminations per pregnancy were analyzed. For this purpose, the hair samples of 150 cattle, born between 2012-2014 in one of the cattle farms of Ferdous Pars company, were used for genotyping based on 30108 SNPs chip. The data were analyzed using the least square variance analysis method using the GLM. GWAS analysis was performed after controlling the quality of the data. The results identified that 2 and 12 SNPs had a significant correlation with calving to insemination interval and interval between first to last insemination traits(p<0.04), respectively. In addition, 11 SNPs and 5 SNPs showed significant correlation for days open and the number of insemination per conception traits (p<0.04), respectively. In the Post-GWAS stage, some Quantitative Trait Loci (QTL) and various genes were identified that affected or controlled the trait. Out of the related NUF2 gene on chromosome 3 affects the development of the oocyte, ANAPC1 gene on chromosome 11, which affects sperm motility, PITX2 gene in chromosome 6, affects milk production and ELOVL6 gene on chromosome 6 affects body weight., it can be concluded that chromosomes 3, 6 and 11 have SNPs that are more strongly related to reproductive traits.
sadeghi, M., maddahi, N., Nejati-Javaremi, A., Miraei-Ashtiani, S. R., & Jalil Sarghale, A. (2024). Genome-Wide Association Studies for Selected Reproductive traits in Iranian Holstein cattle. Iranian Journal of animal Science, (), -. doi: 10.22059/ijas.2023.359774.653947
MLA
mostafa sadeghi; narges maddahi; Ardeshir Nejati-Javaremi; S Reza Miraei-Ashtiani; Ali Jalil Sarghale. "Genome-Wide Association Studies for Selected Reproductive traits in Iranian Holstein cattle". Iranian Journal of animal Science, , , 2024, -. doi: 10.22059/ijas.2023.359774.653947
HARVARD
sadeghi, M., maddahi, N., Nejati-Javaremi, A., Miraei-Ashtiani, S. R., Jalil Sarghale, A. (2024). 'Genome-Wide Association Studies for Selected Reproductive traits in Iranian Holstein cattle', Iranian Journal of animal Science, (), pp. -. doi: 10.22059/ijas.2023.359774.653947
VANCOUVER
sadeghi, M., maddahi, N., Nejati-Javaremi, A., Miraei-Ashtiani, S. R., Jalil Sarghale, A. Genome-Wide Association Studies for Selected Reproductive traits in Iranian Holstein cattle. Iranian Journal of animal Science, 2024; (): -. doi: 10.22059/ijas.2023.359774.653947
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