Iranian Journal of animal Science

Iranian Journal of animal Science

Effect of inactivated Tsukamurella inchonensis on post vaccination serum titer ‎against infectious bursal disease in broiler chicks

Document Type : Research Paper

Authors
Katayoon Nofouzi 1
Monireh Khordadmehr 1
Vahid Reza Ranjbar 2
1 Associate Professor, Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, ‎Tabriz, Iran
2 Ph.D. Graduate, Clinic of Poultry Disease, Yazd Province, Yazd, Iran
10.22059/ijas.2020.304474.653784
Abstract
The present study was designed to investigate the effect of inactivated Tsukamurella inchonensis (T. inchonensis) on the immune response against infectious bursal disease (IBD) vaccination in broiler chicks. Ross broiler chicks in the cage (n= 180; one day old) were randomly assigned to five groups (36 birds in each group). Experimental diets were prepared by adding 106 cells per bird of inactivated T .inchonensis into the commercial basal diet. For group the treatment was continuously dosed during 24 h from day 1 to day 13; and for group 2 during 24 h on days 1 to 5; 8; 9, 12 and 13. Group 3 was received 106 bacteria as subcutaneous injection on days 1, 6, and 12. Groups 4 and 5 weren't received T. inchonensis during the experiment period. Blood was collected on days 1, 14, 28, and 42 from the wing vein of 12 birds, randomly per treatment. Serum IBD antibody titer were studied by ELISA, which measured by double-antibody sandwich ELISA using commercial kits. T. inchonensis treatments, irrespective of the routes of delivery, increased the antibody titers to IBD vaccines, especially when broiler chickens treated with pulse dosed in the feed (p < 0.05). T. inchonensis augmented the effects of IBD vaccination in strengthening subsequent anti-viral responses.
Keywords
Actinomycetes
Immune responses
route of administration
  1. Ali, A.S., Abdalla, M.O. & Mohammed, M.E.H. (2004). Interaction between Newcastle disease and infectious bursal disease vaccines commonly used in Sudan. International Journal of Poultry Science, 3, 300-304.
  2. Anjum, A.D., Sabri, G.S. & Jamshidi, K. (1994). Occurrence spread and control of infectious bursal disease in Pakistan. Proceedings of 1st PPAPVMA Punjab, International Poultry Conference, Punjab, India, March 30 – April 01, 1994, pp. 57-59.
  3. Besseboua, O., Agad, A. & Benbarek, H. (2015). Determination of the optimal time of vaccination against infectious bursal disease virus (Gumboro) in Algeria. Onderstepoort Journal of Veterinary Research, 82 (1), 1-6.
  4. Farooq, M., Durrani, F.R., Imran, N., Durrani, Z. & Chand, N. (2003). Prevalence and economic losses due to infectious bursal disease in broilers in Mirpur and Kolti districts of Kashmir. International Journal of Poultry Science, 2(4), 267-270.
  5. Hermann, M., Rafiqul Islam, M.D. & Raue, R. (2003). Research on infectious bursal disease: The past, the present and the future. Veterinary Microbiology, 97, 153-165.
  6. Hung, C.M., Yeh, C.C., Chong, K.Y., Chen, H.L., Chen, J.Y., Kao, S.T., Yen, C.C., Yeh, M.H., Lin, M.S. & Chen, C.M. (2011). Giango-San enhances immunity and potentiates infectious bursal disease vaccination. Evidence-Based Complementary and Alternative Medicine, 2011:238208.
  7. Mahmood, M.S., Siddique, M., Hussain, I., Khan, A. & Mansoor, M.K. (2006). Protection capability of recombinant plasmid DNA vaccine containing VP2 gene of very virulent infectious bursal disease virus in chickens adjuvanted with CpG oligodeoxynucleotide. Vaccine, 24, 4838-4846.
  8. Mesgari-Abbasi, M., Ghaderi, S., Khordadmehr, M., Nofouzi, K., Tayefi-Nasrabadi, H. & McIntyre, G. (2019). Enteroprotective effect of Tsukamurella inchonensis on streptozotocin induced type 1 diabetic rats. Turkish Journal of Biochemistry, 44 (5), 683-691.
  9. Nofouzi, K., Sheikhzadeh, N., Varshoie, H., khadir-Sharabyani, S., Jafarnezhad, M., Shabanzadeh, S., Ahmadifar, E., Stanford, J. & Shahbazfar, A.A. (2019a). Beneficial effects of killed Tsukamurella inchonensis on rainbow trout growth, intestinal histology, immunological, and biochemical parameters. Fish Physiology and Biochemistry, 45, 209-217.
  10. Nofouzi, K., Hasanzadeh, A., Khordadmehr, M., Madadi, M.S., Ranjbar, V.R. & McIntyre, G. (2019b). Effects of spraying different dietary Killed Tsukamurella inchonensis levels on growth performance, small intestine morphometry, and immune responses in Newcastle disease vaccinated Japanese quails. Journal of Animal Science Researches, 29 (2), 73-89. (In Farsi)
  11. Nofouzi, K., Aghapour, M., Baradaran, B., Hamidian, Gh., Zare, P., Stanford, J., Ripley, P., Tahapour, K., Jafari, K., Shahbazfar, A.A. & Tukmechi, A. (2017). Veterinarni Medicina, 62 (12), 668-673.
  12. Nofouzi, K., Aghapour, M., Hamidian, G.H., Katiraee, F., Stanford, J. & Ripley, P. (2016). Oral administration of heat killed Tsukamurella inchonensis enhances immune responses and intestinal function in mice. Veterinarni Medicina-Czech, 61, 681-688.
  13. Rautenschlein, S., Yeh, H.Y., Njenga, M.K. & Sharma, J.M. (2002). Role of intrabursal T cells in infectious bursal disease virus (IBDV) infection: T cells promote viral clearance but delay follicular recovery. Archives Virology, 147, 285-304.
  14. Safaei, S., Fatahi-Bafghi, M. & Pouresmaeli, O. (2018). Role of Tsukamurella species in human infectious: first literature review. New Microbes New Infect, 22, 6-12.
  15. Schwartz, M.A., Tabet, S.R., Collier, A.C., Wallis, C.K., Carlson, L.C., Nguyen, T.T., Kattar, M.M. & Coyle, M.B. (2002). Central venous catheter-related bacteremia due to Tsukamurella in the immunocompromised host: A case series and review of literature. Clinical Infectious Diseases, 2002: 35e, 72-7.
  16. Shane, S.M., Lasher, H.N. & Paxton, K.W. (1994). Economic impact of infectious bursal disease and prevalence of antigenic variation for protection in infectious bursal disease’, Proceedings of the 2nd International Symposium on infectious bursal to disease (IBD) and chicken infectious anemia (CIA), Rauischholzhausen, Germany, June 21–24, 1994, pp. 196-203.
  17. Stanford, J., Stanford, C. (2012). Mycobacteria and their world. International Journal of Microbiology, 3-12.
  18. Takebe, I., Sawabe, E., Ohkusu, K., Tojo, N., Tohda, S. (2014). Catheter-related bloodstream infection by T. inchonensis in an immunocompromised patient. Journal of Clinical Microbiology, 52 (6), 2251-2253.
  19. Talazadeh, F., Mayahi, M., Nofouzi, K., Golzar, E. & Chegini, R. (2016). The effect of Tsukamurella inchonensis bacterin on the immune resonses against influenza and Newcastle disease vaccines in broiler chickens. International Journal of Enteric Pathogens, 4 (4), e37107.
  20. Talebi, A., Amani, S., Pourmahmod, M., Saghaei, P. & Rezaie, R. (2015). Symbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens. Veterinary Research Forum, 6 (3), 191-197.
  21. Tarres, M.C., Gayol, M., Picena, J.C., Alet, N., Bottasso, O. & McIntyre, G. (2012). Beneficial effects of immunotherapy with extracts derived from Actinomycetales on rats with spontaneous obesity and diabetes. Immunotherapy, 4 (5), 1-11.
  22. Tayade, C., Koti, M. & Mishra, S.C. (2006). L-Arginine stimulates intestinal intraepithelial lymphocyte functions and immune response in chickens orally immunized with live intermediate plus strain of infectious bursal disease vaccine. Vaccine, 24, 5473-5480.
  23. Turner, D. W., Roberson, B.S. & Longton, R.W. (1976). Cell-mediated immune response to products of Actinomyces viscosus cultures. Infection and Immunity, 14 (2), 372-375.
  24. Wigley, P. & Kaiser, P. (2003). Avian cytokines in health and disease. Brazilian Journal of Poultry Science,5, 1-14.
  25. Williams, A.E. & Davision, T.F. (2005). Enhanced immunopathology induced by very virulent infectious bursal disease virus. Avian Pathology, 34 (1), 4-14.
  26. Wu, C.C., Dorairajan, T. & Lin, T.L. (2000). Effect of ascorbic acid supplementation on the immune response of chickens vaccinated and challenged with infectious bursal disease virus. Veterinary Immunology and Immunopathology, 74, 145-152.
  27. Yu, L., Li, J.R., Huang, Y.W., Dikki, J. & Deng, R. (2001). Molecular characteristics of full-length of genomic segment A of three infectious bursal disease viruses in China: two attenuated and a field virulent strain. Avian Diseases, 45, 862-874.

 

Iranian Journal of animal Science
Volume 51, Issue 3
Autumn 2020
Pages 193-199

  • Receive Date 22 June 2020
  • Revise Date 28 July 2020
  • Accept Date 09 August 2020