Effects of tylosin injection in dry period on the performance and serum chemistry in dairy cows after parturition

Document Type : Research Paper

Authors

1 Ph.D. Candidate, Department of Animal Science, Faculty of Agriculture, Univeristy of Zanjan, Zanjan, Iran

2 Professor, Department of Animal Science, Faculty of Agriculture, Univeristy of Zanjan, Zanjan, Iran

3 Professor, University College of Agriculture & Natrual Resources, University of Tehran, Karaj, Iran

4 University Distinguished Professor of Microbiology, Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States

Abstract

To investigate the effects of tylosin injection in dairy cows at dry period on performance, milk composition and some blood parameters in subsequent lactation, 120 Holstein cows with a mean weight of 720±20Kg were used. Treatments were no tylosin (treatment 1; control group), injected 0.025 (treatment 2 low tylosin; LT) and 0.05 (treatment 3 high tylosin; HT) ml tylosin 20% per kg of body weight per day for 3 days after drying days. To determine biochemical parameters blood samples were collected at the drying day and 0, 7, 14, and 21 of lactation. Data of milk production and composition were collected for 4 months after calving. The difference between serum total protein concentration between treatments tended to be significant (P=0.051).  Aspartate aminotransferase (AST) and alkaline phosphatase (ALP) activities were lower in the control group (P<0.05). The activity of creatine kinase (CK) tended to be significant (P=0.053) with tylosin injection. Milk production, milk protein and fat contents, calving parameters and periparturition disorders did not affect by tylosin injection (P>0.05). The incidence of mastitis in the groups receiving tylosin was significantly lower than the control group (P <0.05). Results suggest that tylosin do not cause dramatic changes in serum clinical chemistry profiles, but it was effective in reducing the occurrence of mastitis and had no negative effect on parturition, disorders around it and calf losses until 2 month of age.

Keywords

References

  1. Amanlo, H. & Abozar, M. (2007). In: Cook N. B., Nordland K. V. (2004). Managing the transition cow to optimize health and productivity. Zanjan university publishers co. Zanjan, Iran. (in Farsi)
  2. Ametaje, B. N. (2010). METABOLIC DISORDERS OF DAIRY CATTLE. P:58 Veterinary science: edited by Robert J. Hudson, Ole Nielsen, J. Bellamy, Craig Stephen. Eolss Publishers co. Ltd., United Jingdom.
  3. Ataee, O., Hovareshti, P., Bolourchi, M., Barin, A., Gerami, A. & Niasari-Naslaji A. (2009). Effect of systemic antibacterial administration during prepartum period on coagulase negative Staphylococcal intramammary infection in Holstein Heifers. Iranian Journal of Veterinary Research, Shiraz University, 10(3), 28.
  4. Barton, M. D. (2000). Antibiotic use in animal feed and its impact on human health. Nutrition Research Reviews, 13, 279-299.
  5. Body, J. W., Douglas, T. A., Gould, C. M. & Grimes, F. C. (1964). The interpretation of serum enzyme assay in cattle. Veterinary Record, 76, 567-574.
  6. Brent, H. & Todd, D. (2003): Nutritional and metabolic profile testing of dairy cows. University of Guelph. AHL LabNote, 4, 1-3.
  7. Cavestany, D., Blanc, J. E., Kulcsar, M., Uriarte, G., Chilibroste, P., Meikle, A., Febel, H., Ferraris, A. & Krall, E. (2005). Studies of the transition cow under a pasture-based milk production system: Metabolic profiles. Journal of veterinary medicine. A, Physiology, Pathology, Clinical Medicine, 52, 1-7.
  8. Contreras, B. G. A., Guterbock, W. M., Muñoz, R. J. & Sears, Ph. M. (2013). Comparison of systemic and intramammary dry cow treatments. Revista MVZ Córdoba, 18(1), 3259-3264,
  9. Dore´, E., Fecteau, G., He´lie, P. & Francoz, D. (2007). Liver Abscesses in Holstein Dairy Cattle: 18 Cases (1992–2003). Journal of Veterinary Internal Medicine, 21, 853-856.
  10. FAO. (1991). Residues of some veterinary drugs in animals and foods. FAO Food and Nutrition Paper 41/4.
  11. Gao, X. & Oba, M. (2014). Relationship of severity of subacute ruminal acidosis to rumen fermentation, chewing activities, sorting behavior, and milk production in lactating dairy cows fed a high-grain diet. Journal of Dairy Science, 97, 3006-3016.
  12. Ghada, A.E. M. (2014). Investigation of some enzymes level in blood and milk serum in two stages of milk yield dairy cows at assiut city. Assiut Veterinary Medical Journal, 60(142).
  13. Gonzalez, F. D., Muino, R., Pereira V., Campos R. & Benedito J. L. (2011). Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. Journal of Veterinary Science, 12, 251-255.
  14. Hoffmann, W. E. & Solter, P. F. (2008). Diagnostic enzymology of domestic animals. In: Kaneko, J. J., Harvey, J. W., Bruss, M. L. (ed.), Clinical Biochemistry of Domestic Animals. 6th ed. Elsevier, Burlington, MA, pp. 351-378.
  15. Janosi, Sz. & Huszenicza, G. (2001). The use of the dry cow therapy in the control of bovine mastitis. Veterinari Medincine -Czech, 46(2), 55-60.
  16. Jozghaesemi, Sh., Amanlou, H., Dehghan bonadaki, M. & Nagaraja, T. G. (2017). Liver abscesses in lactating Holstein dairy cows: prevalence and histological and hematological changes. In Press. (in Farsi)
  17. Joźwik, A., Strzałkowska, N., Bagnicka, E., Grzybek, W., Krzyżewski, J., Poławska, E., Kołataj, A. & Horbańczuk, J. O. (2012). Relationship between milk yield, stage of lactation, and some blood serum metabolic parameters of dairy cows. Czech Journal of Animal Science, 57(8), 353-360.
  18. Kayano, M. & Kida, K. (2015). Identifying alterations in metabolic profiles of dairy cows over the past two decades in Japan using principal component analysis. Journal of Dairy Science, 98, 1-11.
  19. Khafipour, E., Krause, D. O. & Plaizier, J. C. (2009). A grain-based subacute ruminal acidosis challenge causes translocation of lipopolysaccharide and triggers inflammation. Journal of Dairy Science, 92, 1060-1070.
  20. Mashhady, A., Ghorbanpour, M., Rasekh, A. & Kazemi, J. (2005).A survey on some Bacteriological and pathological aspects of Cattle liver Abscesses. Scientific Journal of the School of Veterinary Medicine, Shahid Chamren University of Ahvaz, 8th Year, No. 9&10.
  21. Meyer, D. J. & Harvey, J. W. (1998). Evaluation of hepatobiliary system and skeletal muscle and lipid disorders. In: Veterinary Laboratory Medicine. Interpretation and Diagnosis. (Meyer, D. J., J. W. Harvey, Eds.) 2nd ed., W.B. Saunders company Philadelphia, London, Toronto, Montreal, Sydney, Tokyo. pp. 157-187.
  22. Meyer, N. F., Erickson, G. E., Klopfenstein, T. J., Benton, J. R., Luebbe, M. K. & Laudert, S. B. (2015). Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. Journal of Animal Science, 91, 2219-2228.
  23. Mohri, Sharifi, M. K. & Eidi, S., (2007).Hematology and serum biochemistry ofHolstein dairy calves: age related changes and comparison with blood composition in adults. Research in Veterinary Science, T.83. P. 30-39.
  24. Nagaraja, T. G., Laudert, S. B. & Parrott, J. C., (1996). Liver abscesses in feedlot cattle. Part 2. Incidence, economic importance and prevention. Compendium on Continuing Education for the Practising Veterinarian, 18, S264-S273.
  25. Nagaraja, T. G. & Chengappa, M. M. (1998). Liver abscesses in feedlot cattle: A review. Journal of Animal Science, 76: 287-298.
  26. Nocek, J. E. (1997). Bovine Acidosis: Implications on Laminitis. Journal of Dairy Science, 80(5), 1005-1028.
  27. Nagaraja, T. G. & Lechtenberg, K. F. (2007). Acidosis in feedlot cattle. Veterinary Clinics of North America: Food Animal Practice, 23, 333-350.
  28. Oba, M. & Wertz-Lutz, A. E. (2011). RUMINANT NUTRITION SYMPOSIUM: Acidosis: New insights into the persistent problem. Journal of Animal Science, 89, 1090-1091.
  29. Sato, J., Kanata, M., Yasuda, J., Sato, R., Okada, K., Seimiya, Y. & Naito, Y. (2005): Changes of serum alkaline phosphatase activity in dry and lactational cows. Journal of Veterinary Medical Science, 67, 813-815.
  30. Shaver, R. D. (1997). Nutritional Risk Factors in the Aetiology of Left Displaced Abomasum in Dairy Cows: A Review. Journal of Dairy Science, 80, 2449-2453.
  31. Stojesvic, Z., Pirsljin, J., Milinkovic-tur, S., Zdelar-tuk, M. & Beerlubic, B. (2005). Activities of AST, ALT and GGT in clinically healthy dairy cows during lactation and in the dry period. Veterinarski Arhiv, 75, 67-73.
  32. Whitaker, M. A. (1997). Interpretation of metabolic profiles in dairy cows. Cattle Practice, 5, 7-60.
Iranian Journal of animal Science
Volume 48, Issue 3 - Serial Number 3
December 2017
Pages 379-389

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History

  • Receive Date: 23 September 2017
  • Revise Date: 11 October 2017
  • Accept Date: 08 November 2017

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