Investigating the effect of cottonseed bioactive peptides and organic zinc supplementation in the close-up diet on the immune status, blood metabolites and milk production of Holstein fresh cows

Articles in Press

Document Type : Research Paper

Authors

1 PhD. Candidate, Department of Animal Science, Faculty of Agriculture, University of Zanjan, Zanjan

2 Department of Animal Science, Faculty of Agriculture, University of Zanjan, Zanjan, Iran

3 Biosystem Engineering Department , Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.

4 talise nemone dairy farm

Abstract

The aim of this research was to investigate the effects of cottonseed bioactive peptides and organic zinc supplementation in the prepartum diet on the immune response and milk production of Holstein fresh cows. A total of one hundred and eighty multiparous Holstein cows were divided into four experimental groups: 1) Basal diet without peptide Pe0Zn0 ; 2) Basal diet with 300 g of bioactive peptide Pe1Zn0; 3) Basal diet with 160 mg organic zinc per kg dry matter and without bioactive peptides Pe0Zn1 and 4) Basal diet with 160 mg organic zinc per kg dry matter and 300 g bioactive peptide Pe1Zn1. The inclusion of peptides in the diets led to a notable increase in total antioxidant capacity and glutathione peroxidase concentrations, while simultaneously reducing insulin and Tendency to decrease glucose levels in the postpartum period (P < 0.01). Furthermore, the addition of cottonseed bioactive peptides (P = 0.06) and organic zinc (P < 0.01) to the experimental diet led to a substantial increase in milk production and 3.5% fat corrected milk. Specifically, the incorporation of organic zinc into the prepartum diet resulted in a significant rise in milk fat, protein and lactose percent and milk solids content among fresh cows (P < 0.01). Overall, the supplementation of cottonseed bioactive peptides and organic zinc in the prepartum diets of cows proved to enhance the immune status and production of fresh cows

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Iranian Journal of animal Science

Articles in Press, Accepted Manuscript
Available Online from 30 April 2025

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History

  • Receive Date: 10 March 2025
  • Revise Date: 10 April 2025
  • Accept Date: 19 April 2025

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