پردیس کشاورزی و منابع طبیعی دانشگاه تهران Iranian Journal of animal Science 2008-4773 56 3 2025 09 23 The effects of feeding different levels of Lipidol as starter feed additive on growth performance, health, fat digestibility and blood and ruminal parameters of Holstein calves The effects of feeding different levels of Lipidol as starter feed additive on growth performance, health, fat digestibility and blood and ruminal parameters of Holstein calves 489 507 101462 10.22059/ijas.2025.384035.654033 FA Sadegh Farzi Department of Animal Science, Faculty of Agriculture and Natural Resources, University of Tehran, Karaj, Iran 0009-0009-6195-9526 Mehdi Dehghan Banadaky Department of animal science- faculty of agriculture and natural resources- University of Tehran, Karaj. Iran 0000-0001-8448-1371 Kamran Rezayazdi Department of animal science- faculty of agriculture and natural resources- University of Tehran- Karaj- Iran 0000-0002-1835-8612 Mehdi Ganjkhanlou Department of Animal Science, Faculty of Agriculture and Natural Resources, University of Tehran, Karaj, Iran 0000-0002-1854-321X Masoud Alimirzaei Aras-Dam Arsham Co., poldasht, west Azarbayjan, Iran 0000-0001-6455-0747 Journal Article 2024 11 09 The aim of this study was to evaluate the effect of feeding different levels of lipidol (containing active lysophospholipids and lecithin) as starter feed additive on performance of Holstein calves. Forty colostrum fed calves from 3 days of age were randomly assigned to a completely randomized design on d 3 of age. Treatments included starter feed without lipidol (STL0) and 0.05% (STL0.5), 0.1% (STL1) and 0.2% (STL2) lipidol as DM basis. All calves were housed individually and had free access to starter feed and fresh water throughout the study. Dry matter intake from starter diet was greater in STL2 group than the other groups (p = 0.04) throughout the study. Fat digestibility increased linearly as the lipidol concentration increased, with significant difference between STL2 and control groups ( P < 0.05). Average daily gain (ADG) tended to be significant difference in calves fed STL0.5 and STL2 diet (p= 0.08 ) during the early post weaning period. Glucose concentration tended to be increased in STL2 calves relative to other counterparts (p = 0.08). Also, a greater concentration of total protein and albumin was found for STL2 calves on d 28. Control calves had elevated levels of NEFA in the plasma samples than those fed lipidol additive on d 60 of study, indicating the effectiveness of this additive on fat metabolism and energy. Overall, it can be concluded that supplementing pre-weaned calves starter diet with 0.2 % lipidol as DM may improve the performance of calves during pre and early post-weaning periods. The aim of this study was to evaluate the effect of feeding different levels of lipidol (containing active lysophospholipids and lecithin) as starter feed additive on performance of Holstein calves. Forty colostrum fed calves from 3 days of age were randomly assigned to a completely randomized design on d 3 of age. Treatments included starter feed without lipidol (STL0) and 0.05% (STL0.5), 0.1% (STL1) and 0.2% (STL2) lipidol as DM basis. All calves were housed individually and had free access to starter feed and fresh water throughout the study. Dry matter intake from starter diet was greater in STL2 group than the other groups (p = 0.04) throughout the study. Fat digestibility increased linearly as the lipidol concentration increased, with significant difference between STL2 and control groups ( P < 0.05). Average daily gain (ADG) tended to be significant difference in calves fed STL0.5 and STL2 diet (p= 0.08 ) during the early post weaning period. Glucose concentration tended to be increased in STL2 calves relative to other counterparts (p = 0.08). Also, a greater concentration of total protein and albumin was found for STL2 calves on d 28. Control calves had elevated levels of NEFA in the plasma samples than those fed lipidol additive on d 60 of study, indicating the effectiveness of this additive on fat metabolism and energy. Overall, it can be concluded that supplementing pre-weaned calves starter diet with 0.2 % lipidol as DM may improve the performance of calves during pre and early post-weaning periods. https://ijas.ut.ac.ir/article_101462_8cdf8fcef73001f146d0ac6f4c5fd665.pdf